抑郁症通过AVP-AHI1-Tyk2损害抗病毒先天免疫功能

Depression compromises antiviral innate immunityvia the AVP-AHI1-Tyk2 axis

载有三氧化二砷的脐带细胞外囊泡通过将炎性巨噬细胞重置为M2表型来降低急性移植物抗宿主病的严重程度

hUC-EVs-ATO reduce the severity of acute GVHD by resetting inflammatory macrophages toward the M2 phenotype

HPV-CCDC106整合促进了HPV E6剪接后CCDC106的高表达，从而促进了宫颈癌的进展

HPV-CCDC106 integration promotes cervical cancer progre- ssion by facilitating high expression of CCDC106 after HPV E6 splicing

LncRNA CTBP1-DT编码的蛋白DDUP维持DNA损伤响应信号以触发双重DNA修复机制

LncRNA CTBP1-DT-encoded microprotein DDUP sustains DNA damage response signalling to trigger dual DNA repair mechanisms

线粒体裂变通过降低MHC-I表面表达诱导实体瘤免疫逃逸

Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression

溶酶体跨膜蛋白5通过调节BMPR1A溶酶体降解促进肺特异性转移

Lysosomal protein transmembrane 5 promotes lung-specific metastasis by regulating BMPR1A lysosomal degradation

SHF通过破坏STAT3二聚化作为多形性胶质母细胞瘤的新型肿瘤抑制剂

SHF acts as a novel tumor suppressor in glioblastoma multiforme by disrupting stat3 dimerization

SHF通过破坏STAT3二聚化作为多形性胶质母细胞瘤的新型肿瘤抑制剂

SHF acts as a novel tumor suppressor in glioblastoma multiforme by disrupting stat3 dimerization

琥珀酰化抑制细胞外基质蛋白原纤维蛋白1的酶促水解并促进胃癌发展

Succinylation Inhibits the Enzymatic Hydrolysis of the Extracellular Matrix Protein Fibrillin 1 and Promotes Gastric Cancer Progression

ASCL2通过ATG9B维持干性表型并使胶质瘤对自噬抑制剂敏感

ASCL2 Maintains Stemness Phenotype through ATG9B and Sensitizes Gliomas to Autophagy Inhibitor